The Washington Post's Chris Cillizza reports there's another big pick-up opportunity for the GOP in November:

Indiana Sen. Evan Bayh will not seek re-election this year, a decision that hands Republicans a prime pickup opportunity in the middle of the country.

"After all these years, my passion for service to my fellow citizens is undiminished, but my desire to do so by serving in Congress has waned," Bayh will say.

Bayh will announce the decision at a press conference later today.

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