Moments ago, the cloture vote on the Defense Authorization bill, which included a repeal of the "Don't Ask, Don't Tell" policy on gays in the military and the DREAM Act, failed on what was almost a straight party-line vote. Forty Republican senators, including moderates Olympia Snowe and Susan Collins of Maine, voted against cutting off debate on the bill. (Lisa Murkowski missed the vote).
Blanche Lincoln and Mark Pryor of Arkansas were the only Democrats to vote with the Republicans (if you don't count Harry Reid, who switched his vote to "no" as a procedural matter, so he can bring the bill up for a vote again).
Correction: I initially reported that Blanche Lincoln was the only Democrat to vote with the Republicans.