C.K. MacLeod writes at Hot Air:
Dismantling, impeding, nullifying, and, in the end, fully repealing this bill does not require 60 Republicans or 60 conservatives: Greater legal, legislative, and historical minds than mine must already be studying the precedents and gaming the scenarios, but we can observe here that, if passing popular legislation in the Senate always required partisan super-majorities, we wouldn't have had a major piece of legislation signed since 1979. We don't know yet how the final votes in the Senate or for final passage after a House-Senate conference may go, but reversing them down the road would merely require a popularly backed majority joined by a passel of fence-sitters, perhaps including Democratic senators who in the current session vote for cloture but against final passage, perhaps including a few changes of heart. It could be as simple as that. ...
Moreover, it's well worth keeping in mind that removing the budgetary heart of the bill can be achieved via the Senate reconciliation process on a simple, unfilibusterable 51-vote majority (especially easy to justify if Obamacare finally passes on party line votes as narrow as Pelosicare's in the House). If virtual repeal on this basis looks achievable as early as, say, 2011, the President might veto an O-care-destroying budget, while hoping for a re-play of the Clinton-Gingrich government shutdown confrontation of 1995, but such a battle could unfold in many different ways.
Another way to put it: Passing a multi-trillion dollar government takeover of health care supported by only 35 percent of the public takes 60 Democratic senators; repealing such a monstrosity does not. Though it will take many many more Republicans in the House and Senate than there are now.